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Nitrogen coordinated import and export of arginine across the yeast vacuolar membrane

Author summary The lysosome-like vacuole of the yeast Saccharomyces cerevisiae is an important storage compartment for diverse nutrients, including the cationic amino acid arginine, which accumulates at high concentrations in this organelle in nitrogen-replet…

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Microsoft releases new patch for Windows 10 October 2020 Update (20H2)

Four days ago, Microsoft started to roll out what it thought would be the final release for Windows 10 20H2 (October 2020 Update as it’s also known) to Insiders…

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Four days ago, Microsoft started to roll out what it thought would be the final release for Windows 10 20H2 (October 2020 Update as its also known) to Insiders in the Beta and Release Preview Channels — Build 19042.508 (KB4571756).
Today it updates that ‘final’ build to 19042.541, fixing a massive list of issues.
Changes in this build include:

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Looking to Quarantine Remotely? These Private Islands Take Seclusion to the Next Level

Does the ongoing COVID-19 pandemic have you pining for someplace far from the maddening crowds? Can you work remotely, as in really remotely? Well, for those wh…

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Does the ongoing COVID-19 pandemic have you pining for someplace far from the maddening crowds? Can you work remotely, as in really remotely? Well, for those who dream of the ultimate escape or seek a seriously secluded hideaway, you’ll be pleased to know that you can escape to your own private island — at least you can if you’ve got the funds.
Marlon Brando pioneered private island acquisition in 1966, when the Tahitian government granted him a 99-year lease on Tetiaroa, making him the de fact…

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Your ultimate guide to American Airlines AAdvantage

American Airlines AAdvantage miles have devalued over the last few years, but you can still get a ton of value out of the program.  And now might be the time to…

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American Airlines AAdvantage miles have devalued over the last few years, but you can still get a ton of value out of the program. 
And now might be the time to do so. American has made several consumer-friendly changes in recent months, including extending elite status for AAdvantage members, eliminating most change fees and pausing mileage expiration through the end of 2020. If youre thinking of jumping ship to American, theres a lot youll need to know before you start earning and redeeming A…

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